Synthesis of Novel N1 and N2 Indazole Derivatives

Autor: Prasanna Bethanamudi, Srinivas Bandari, Kanakaraju Sankari, Amarnath Velidandi, G. V. P. Chandramouli
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: E-Journal of Chemistry, Vol 9, Iss 4, Pp 1676-1682 (2012)
Druh dokumentu: article
ISSN: 0973-4945
2090-9810
55302335
DOI: 10.1155/2012/165784
Popis: The alkylation of 5-cyano indazoles 2 in the presence of readily available imidizolium salts (ionic liquids) (Bmim)BF4 as phase transfer catalyst were performed to afford the regio isomers N1-and N2-(substituted alkyl)-5-cyano indazoles. The N1-alkylated cyano indazoles were converted to the corresponding N1-(substituted alkyl)-5-aminomethyl and 5-carbaldehydes 5(a-f) and 6(a-f).
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