| Autor: |
Felipe González Martínez, María Isabel González Sánchez, Jimena Pérez-Moreno, Blanca Toledo del Castillo, Rosa Rodríguez Fernández |
| Jazyk: |
Spanish; Castilian |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Anales de Pediatría (English Edition), Vol 91, Iss 2, Pp 112-119 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2341-2879 |
| DOI: |
10.1016/j.anpede.2018.11.013 |
| Popis: |
Introduction: High-flow nasal cannula (HFNC) is a safe and effective treatment in bronchiolitis in paediatric wards. The optimal flow on starting HFNC is still unknown. The main aim of this study was to determine if there were differences in clinical outcome of patients according the initial flow. Methods: A prospective, observational and analytical study was conducted between 2014 and 2016 on infants admitted with bronchiolitis and who required HFNC. Two cohorts were established according to the initial flow: cohort 1: flow 15 L/min (HFNC-15), and cohort 2: flow 10 L/min (HFNC-10). Treatment failure was defined as the presentation of apnoea or the absence of clinical improvement in the first 12–24 h. Multivariate probabilistic models were built to identify predictive variables of treatment failure. Results: A total of 57 patients were included. The median age was 4 months (IQR 2–13), and 54% received treatment with HFNC-10 and 46% with HFNC-15. In HFNC-15 cohort, respiratory rate (RR) decreased in the first hour, and in the HFNC-10 cohort in the first 6 h (P = .03). In HFNC-10 cohort, treatment failure rate was 71%, compared to 15% of HFNC-15 (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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