A Unique Constellation of Multiple Cranial Neuropathies in a Patient with Preeclampsia

Autor: Pardis Zarifkar, Klaus Hansen, Clarissa Crone, Kirsten Svenstrup, Vibeke Andrée Larsen, William Kristian Karlsson
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Case Reports in Neurology, Vol 14, Iss 2, Pp 256-260 (2022)
Druh dokumentu: article
ISSN: 1662-680X
DOI: 10.1159/000524459
Popis: A 36-year-old nullipara at 35 weeks of gestation woke up with slurred speech and dysphagia. The next day, she developed abruption of the placenta, underwent an acute cesarean, and was diagnosed with severe preeclampsia. Neurologic examination revealed flaccid dysarthria, bilateral soft palate palsy, reduced taste of the left posterior tongue, left-sided tongue deviation, and paralysis of the left sternocleidomastoid and trapezius muscles. MRI revealed left-sided tongue edema compatible with acute left hypoglossal nerve denervation and electromyography of the left trapezius and glossal muscles showed profuse denervation potentials. In conclusion, multiple cranial neuropathies may occur in and even be a presenting symptom of preeclampsia. In this study, we report the first case of multiple cranial neuropathies involving cranial nerves IX, X, XI, and XII in a patient with preeclampsia. Possible pathogenic mechanisms of cranial neuropathy in preeclampsia include immune-mediated neuropathy with or without demyelination, microvascular thromboses, and perineural edema.
Databáze: Directory of Open Access Journals
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