Autor: |
Annette K Regan, Prakesh S Shah, Sandra I Dunn, Ann E Sprague, Deshayne B Fell, Mark C Walker, Jeffrey C Kwong, Sarah A Buchan, Jon Barrett, Darine El-Chaâr, Eszter Török, Sarah E Wilson, Shannon E MacDonald, Sheryll Dimanlig-Cruz, Gillian D Alton, Tavleen Dhinsa, Nannette Okun, Liam Bruce |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
BMJ Medicine, Vol 2, Iss 1 (2023) |
Druh dokumentu: |
article |
ISSN: |
2754-0413 |
DOI: |
10.1136/bmjmed-2023-000632 |
Popis: |
Objective To assess risk of adverse pregnancy, fetal, and neonatal outcomes after a third dose (first booster dose) of covid-19 vaccine during pregnancy among individuals who had completed both doses of primary covid-19 vaccine series before pregnancy.Design Population based, retrospective cohort study.Setting Ontario, Canada, from 20 December 2021 to 31 August 2022.Participants Individuals were included if they were pregnant with an expected date of delivery from 20 December 2021 (start date of third dose eligibility for everyone ≥18 years) to 31 August 2022, who had completed the two doses of primary covid-19 messenger RNA vaccine series before pregnancy, and became eligible for a third dose (≥six months since dose two) before the end of pregnancy.Main outcome measures Pregnancy outcomes included hypertensive disorders of pregnancy, placental abruption, caesarean delivery, chorioamnionitis, and postpartum hemorrhage. Fetal and neonatal outcomes included stillbirth, preterm birth, admission to neonatal intensive care unit for >24 h, newborn 5 min Apgar score |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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