Sleep Disorders and Quality of Life in Patients With Cancer: Prospective Observational Study of the Rafael Institute

Autor: Nathaniel Scher, Liath Guetta, Clément Draghi, Safia Yahiaoui, Mathilde Terzioglu, Emilie Butaye, Kathy Henriques, Marie Alavoine, Ayala Elharar, Andre Guetta, Alain Toledano
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: JMIR Formative Research, Vol 6, Iss 11, p e37371 (2022)
Druh dokumentu: article
ISSN: 2561-326X
DOI: 10.2196/37371
Popis: BackgroundSleep disorders are a common occurrence in the general population. Yet today, it is clearly agreed that sleep disorders represent both a cancer risk factor and a biological consequence of the of the activation of the immuno-inflammatory system induced by cancer itself. ObjectiveThe aim of this study was to assess the impact of sleep disorders on quality of life and identify the type of disorder and its causes in order to offer an adapted and personalized care plan. MethodsIn a survey completed during the COVID-19 lockdown, 2000 hours of interviews were collected by remote consultations. During these calls, we administered a sleep questionnaire. This questionnaire was inspired by the STOP-BANG questionnaire and enquired about 6 items. The demographic details of each patient (eg, age and sex), the nature of the pathology, their past treatments, the ongoing cancer treatment, the mood, whether or not the patient is anxious or depressed, and the use of sleeping drug pills were analyzed. A univariate analysis was performed according to the presence or absence of fatigue. Chi-square test was applied to assess possible differences of variables’ link to sleep disturbance between patients complaining of fatigue and those without fatigue. The same test was then used to analyze patients on hormone therapy and those with no hormone therapy for 2 types of cancer—breast cancer and prostate cancer. ResultsA total of 905 patients were prospectively included in this study. The average age was 66.7 (5 SD) years, and 606 (67%) patients were women; 142 patients declared being overweight. Breast cancer was the most frequently reported cancer. Nocturnal awakening was reported by 70% (n=633), fatigue by 50% (n=452), difficulty falling asleep by 38% (n=343), snoring reported by an independent observer in 38% (n=343), and apnea reported by an independent observer in 9% (n=81) of the patients. The univariate analysis showed that the feeling of tiredness was significantly greater in patients reporting difficulty falling asleep (P≥.99), pain (P
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