MEDICINE AND THE LAW
| Autor: | A Bangalee, S Hanley, V Bangalee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | South African Medical Journal, Vol 112, Iss 10 (2022) |
| Druh dokumentu: | article |
| ISSN: | 0256-9574 2078-5135 |
| DOI: | 10.7196/SAMJ.2022.v112i10.16596 |
| Popis: | Dolutegravir (DTG) is a pivotal antiretroviral medicine that has become the backbone of several HIV programmes, especially in sub-Saharan African countries. It has recently replaced efavirenz as the preferred third drug for people initiating antiretroviral therapy in South Africa (SA). Its tolerability, cost-effectiveness and favourable resistance profile have had a global influence on HIV management, including the recent revision of the World Health Organization antiretroviral guidelines. As with any medicine, however, informed decisions are important. Despite the several advantages DTG offers, additional data informing risks over benefits have emerged that warrant clinical attention before DTG is prescribed. This article aims to give the primary care provider an overview of the benefits and risks associated with the roll-out of DTG in SA. |
| Databáze: | Directory of Open Access Journals |
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