| Autor: |
Mika Kivimäki, ProfPhD, Eeva Kuosma, MSc, Jane E Ferrie, PhD, Ritva Luukkonen, PhD, Solja T Nyberg, MSc, Lars Alfredsson, ProfPhD, G David Batty, PhD, Eric J Brunner, PhD, Eleonor Fransson, PhD, Marcel Goldberg, ProfMD, Anders Knutsson, ProfPhD, Markku Koskenvuo, MD, Maria Nordin, PhD, Tuula Oksanen, PhD, Jaana Pentti, MSc, Reiner Rugulies, ProfPhD, Martin J Shipley, MSc, Archana Singh-Manoux, PhD, Andrew Steptoe, ProfPhD, Sakari B Suominen, MD, Töres Theorell, ProfMD, Jussi Vahtera, ProfMD, Marianna Virtanen, ProfPhD, Peter Westerholm, ProfMD, Hugo Westerlund, ProfPhD, Marie Zins, MD, Mark Hamer, ProfPhD, Joshua A Bell, PhD, Adam G Tabak, PhD, Markus Jokela, PhD |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
The Lancet Public Health, Vol 2, Iss 6, Pp e277-e285 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2468-2667 |
| DOI: |
10.1016/S2468-2667(17)30074-9 |
| Popis: |
Summary: Background: Although overweight and obesity have been studied in relation to individual cardiometabolic diseases, their association with risk of cardiometabolic multimorbidity is poorly understood. Here we aimed to establish the risk of incident cardiometabolic multimorbidity (ie, at least two from: type 2 diabetes, coronary heart disease, and stroke) in adults who are overweight and obese compared with those who are a healthy weight. Methods: We pooled individual-participant data for BMI and incident cardiometabolic multimorbidity from 16 prospective cohort studies from the USA and Europe. Participants included in the analyses were 35 years or older and had data available for BMI at baseline and for type 2 diabetes, coronary heart disease, and stroke at baseline and follow-up. We excluded participants with a diagnosis of diabetes, coronary heart disease, or stroke at or before study baseline. According to WHO recommendations, we classified BMI into categories of healthy (20·0–24·9 kg/m2), overweight (25·0–29·9 kg/m2), class I (mild) obesity (30·0–34·9 kg/m2), and class II and III (severe) obesity (≥35·0 kg/m2). We used an inclusive definition of underweight ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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