Tibiofemoral joint structural change from 2.5 to 4.5 years following ACL reconstruction with and without combined meniscal pathology

Autor: Xinyang Wang, Kim L. Bennell, Yuanyuan Wang, Tim V. Wrigley, Ans Van Ginckel, Karine Fortin, David J. Saxby, Flavia M. Cicuttini, David G. Lloyd, Christopher J. Vertullo, Julian A. Feller, Tim Whitehead, Price Gallie, Adam L. Bryant
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: BMC Musculoskeletal Disorders, Vol 20, Iss 1, Pp 1-11 (2019)
Druh dokumentu: article
ISSN: 1471-2474
DOI: 10.1186/s12891-019-2687-9
Popis: Abstract Background People who have had anterior cruciate ligament reconstruction (ACLR) are at a high risk of developing tibiofemoral joint (TFJ) osteoarthritis (OA), with concomitant meniscal injury elevating this risk. This study aimed to investigate OA-related morphological change over 2 years in the TFJ among individuals who have undergone ACLR with or without concomitant meniscal pathology and in healthy controls. A secondary aim was to examine associations of baseline TFJ cartilage defects and bone marrow lesions (BML) scores with tibial cartilage volume change in ACLR groups. Methods Fifty seven ACLR participants aged 18–40 years (32 isolated ACLR, 25 combined meniscal pathology) underwent knee magnetic resonance imaging (MRI) 2.5 and 4.5 years post-surgery. Nine healthy controls underwent knee MRI at the ~ 2-year intervals. Tibial cartilage volume, TFJ cartilage defects and BMLs were assessed from MRI. Results For both ACLR groups, medial and lateral tibial cartilage volume increased over 2 years (P
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