Autor: |
James M. Dunce, Amy E. Milburn, Manickam Gurusaran, Irene da Cruz, Lee T. Sen, Ricardo Benavente, Owen R. Davies |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/s41467-018-07794-7 |
Popis: |
The meiotic telomere complex (MAJIN, TERB1, TERB2) tethers telomere ends to the nuclear envelope. Here the authors present the crystal structure of human MAJIN-TERB2 and combine biophysical approaches and structured illumination microscopy analysis of mouse meiotic chromosomes to characterize the molecular architecture of the wider MAJIN-TERB2-TERB1 complex and its interactions with TRF1. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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