ANTIMICROBIAL SUSCEPTIBILITY OF CLINICALLY SIGNIFICANT ISOLATES OF ENTEROBACTER SPP., OBTAINED FROM PATIENTS, HOSPITALISED IN VARNA UNIVERSITY HOSPITAL DURING THE PERIOD 2014 – 2016

Autor: Dobromira Dimitrova, Temenuga Stoeva, Rumyana Markovska, Petya Stankova, Milena Bozhkova, Gergana Nedelcheva, Ivan Mitov
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of IMAB, Vol 23, Iss 4, Pp 1828-1833 (2017)
Druh dokumentu: article
ISSN: 1312-773X
DOI: 10.5272/jimab.2017234.1828
Popis: Purpose: Rapidly increasing antimicrobial resistance in medically important bacterial species from family Enterobacteriaceae is one of the most significant microbiological, clinical and epidemiological issues of modern medicine. The aim of this study is to investigate the antibiotic susceptibility of clinically significant isolates of Enterobacter spp., obtained from patients, hospitalized in University Hospital “Saint Marina” – Varna during the period 2014 – 2016. Material and methods: a total of 433 clinical isolates of Enterobacter spp.from blood cultures, urine and wound secretions were studied. The species identification was made by conventional, semi-automated (Crystal, BD) and automated systems (Phoenix, BD). The susceptibility to piperacillin/tazobactam (TZP), ceftazidime (CAZ), meropenem (MEM), gentamicin (Gm), amikacin (Ak), ciprofloxacin (CIP), levofloxacin (LVX), trimethoprime/sulfamethoxazole (SXT) and tetracycline (Tet) was tested by disc-diffusion method and / or automated system Phoenix 100, BD. The results were interpreted according to EUCAST 2016 guidelines. Results: The resistance in the studied collection of isolates, shown in increasing order is as follows: Аk, 4.2%
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