Serum folate deficiency and associated factors among pregnant women in Haramaya District, Eastern Ethiopia: a community-based study

Autor: Masresha Tessema, Temam Beshir Raru, Kedir Teji Roba, Meseret Woldeyohannes, Newas Yusuf Mamme, Hirbo Shore Roba, Meseret Belete Fite, Gemechu Asefa, Jemal Abrahim, Mohammed Yuya, Tara Wilfong, Demiraw Bikila Gurmu, Feyissa Challa Waka, Wossene Habtu, Mohammed Abdurke Kure, Dawit Alemayehu, Aboma Motuma
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open, Vol 13, Iss 5 (2023)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2022-068076
Popis: Objectives We aimed to estimate the prevalence of folate deficiency and contributing factors among pregnant women.Design A community-based, cross-sectional study.Setting Haramaya District, Eastern Ethiopia.Participants Four hundred and forty-six pregnant women participated in the study.Primary outcome measure The prevalence of folate deficiency and risk factors.Results Overall, the prevalence of folate deficiency was 49.3% (95% CI 44.6% to 54.1%). Pregnant women with iron deficiency anaemia were 2.94 times more likely to develop folate deficiency (adjusted OR (AOR)=2.9, 95% CI 1.9 to 4.7). Respondents with good knowledge of folate-rich foods (AOR=0.3, 95% CI 0.1 to 0.7) and those who took iron and folic acid supplementation (AOR=0.6, 95% CI 0.4 to 0.9) during their pregnancy were less likely to develop folate deficiency.Conclusions In this study, a considerable proportion of pregnant women had folate deficiency during their pregnancy. Therefore, it is critical that nutritional treatment, education and counselling be strengthened to facilitate iron and folic acid supplementation during pregnancy.
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