Activation of M1 muscarinic acetylcholine receptors by proline-rich oligopeptide 7a

Autor: Carlos Alberto-Silva, Halyne Queiroz Pantaleão, Brenda Rufino da Silva, Julio Cezar Araujo da Silva, Marcela Bermudez Echeverry
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 30 (2024)
Druh dokumentu: article
ISSN: 1678-9199
DOI: 10.1590/1678-9199-jvatitd-2023-0043
Popis: Abstract Background: The bioactive peptides derived from snake venoms of the Viperidae family species have been promising as therapeutic candidates for neuroprotection due to their ability to prevent neuronal cell loss, injury, and death. Therefore, this study aimed to evaluate the cytoprotective effects of a synthetic proline-rich oligopeptide 7a (PRO-7a;
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