The predictors of unsuppressed viremia among PLHIV: a cross-sectional study in Ghana

Autor: Lydia Boampong Owusu, Christiana Ababio, Selina Boahene, Abdul-Fatawu Suglo Zakaria, Abigael Omowumi Emikpe, Catherine Kroamah Dwumfour, Kofi Antwi Appiagyei, Felix Apiribu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMC Public Health, Vol 23, Iss 1, Pp 1-10 (2023)
Druh dokumentu: article
ISSN: 1471-2458
DOI: 10.1186/s12889-023-16032-9
Popis: Abstract Background Unsuppressed viremia in HIV infected patients is generally associated with increased rates of disease transmission and poor patient survival. This study assessed the socio-demographic determinants of People Living with HIV/AIDS, having viral load non-suppression and who are receiving antiretroviral therapy in a District Hospital in Ghana. Methods The study utilized the cross-sectional research design with both primary and secondary data conducted from September to October 2021 in Ghana. Data were collected from 331 PLHIV who were placed on Anti-Retroviral Therapy (ART) for more than 12 months at the ART centre at a District Hospital in Ghana. Unsuppressed viremia was defined as plasma viral load of ≥ 1000 copies/mL after 12 months on an ART with effective adherent support. A structured questionnaire was used to collect primary data on participants and a Secondary data was also collected from patients’ folders, hospital registers and the computerized health information systems at the study site. SPSS was used to analyse descriptive and inferential data. Pearson’s chi-square and Fisher’s exact test were used to assess the independent determinants of viral load non-suppression. Pearson’s chi-square test was used for tests giving ≤ 20% of expected cell counts less than five while Fisher’s exact test was used for tests giving > 20% of expected cell counts less than five. A p value of
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