Estrogens as Antioxidant Modulators in Human Fertility

Autor:	A. Mancini, S. Raimondo, M. Persano, C. Di Segni, M. Cammarano, G. Gadotti, A. Silvestrini, A. Pontecorvi, E. Meucci
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	International Journal of Endocrinology, Vol 2013 (2013)
Druh dokumentu:	article
ISSN:	1687-8337 1687-8345
DOI:	10.1155/2013/607939
Popis:	Among treatments proposed for idiopathic male infertility, antiestrogens, like tamoxifen, play a possible role. On the other hand, oxidative stress is a mechanism well recognized for deleterious effects on spermatozoa function. After reviewing the literature on the effects of estrogens in modulation of antioxidant systems, in both sexes, and in different in vivo and in vitro models, we suggest, also on the basis of personal data, that a tamoxifen treatment could be active via an increase in seminal antioxidants.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7924e2d7d50f48cc9399aab609abccaf Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF