Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

Autor: Sigrid Gouma, Kangchon Kim, Madison E. Weirick, Megan E. Gumina, Angela Branche, David J. Topham, Emily T. Martin, Arnold S. Monto, Sarah Cobey, Scott E. Hensley
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-020-18465-x
Popis: Influenza exposure in early childhood can affect the immune response to distinct viral strains later in life. Here, Gouma et al. show that contemporary 3c2.A H3N2 virus infections boost non-neutralizing H3N2 antibodies in middle-aged individuals, potentially leaving them vulnerable to recurrent infections.
Databáze: Directory of Open Access Journals