Analyzing HALP and PNI scores as prognostic factors in metastatic head and neck cancers

Autor: Yakup Duzkopru, Abdulkadir Kocanoglu, Mehmet Yigitbay, Ozlem Dogan, Hayriye Sahinli, Dogan Yazilitas
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Asian Journal of Surgery, Vol 47, Iss 12, Pp 5101-5105 (2024)
Druh dokumentu: article
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2024.04.093
Popis: Objective: This study investigates the prognostic significance of Hemoglobin, Albumin, Lymphocyte, Platelet (HALP) score and Prognostic Nutritional Index (PNI) in metastatic head and neck cancers. Methods: Retrospective analysis was conducted on data obtained from January 2014 to June 2022 for 68 patients using rigorous statistical methods. HALP and PNI scores, derived from routine laboratory parameters, were categorized into low and high groups using respective median values. Prognostic significance was determined through Kaplan–Meier survival analyses and Cox proportional hazards regression using IBM SPSS Statistics. Results: Of the 68 patients (80.9% male, median age 57), 39 (57.4%) had laryngeal cancer. When stratified by low and high HALP scores, the median overall survival (OS) was 5.9 and 16.4 months, respectively (P
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