Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Autor: Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Monica Zhong, Alexandra M. Smink, Bart J. de Haan, Paul de Vos, Kevin Keane, Andreas Vegge, Esther Y. Chen, Wei Song, Wendy F. Liu, James Flanders, Claude Rescan, Lars Groth Grunnet, Xi Wang, Minglin Ma
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-13238-7
Popis: Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.
Databáze: Directory of Open Access Journals