Photoreceptor contributions to the human pupil light reflex

Autor: Pablo A. Barrionuevo, Luis A. Issolio, Constanza Tripolone
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Photochemistry and Photobiology, Vol 15, Iss , Pp 100178- (2023)
Druh dokumentu: article
ISSN: 2666-4690
DOI: 10.1016/j.jpap.2023.100178
Popis: The pupil reacts to the amount of light reaching the eye. It reduces its size when the light is high and dilates at low light levels to allow the entrance of more photons. This behavior is called pupil light reflex (PLR). Recent investigations in humans were conducted to understand how the photoreceptor signals are combined to drive the pupil light reflex. This review is about the physiological processes that govern the pupil in humans. In particular, how cone-opsins, rhodopsin, and melanopsin photoreception contribute to governing the PLR. We also summarize investigations on the assessment of the PLR in clinical settings.
Databáze: Directory of Open Access Journals