Resective Epilepsy Surgery, QUality of life and Economic evaluation (RESQUE): the change in quality of life after resective epilepsy surgery–protocol for a multicentre, prospective cohort study

Autor: Sander van Kuijk, Ghislaine A P G van Mastrigt, Govert Hoogland, Kim Rijkers, Jim Dings, Sandra M A van der Salm, Ilse E C W van Straaten, Julia T F Kellenaers, Olaf E M G Schijns, Marielle C G Vlooswijk, Louis G L Wagner, Sander Idema, Marian H J M Majoie
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open, Vol 13, Iss 7 (2023)
Druh dokumentu: article
ISSN: 2022-0642
2044-6055
DOI: 10.1136/bmjopen-2022-064263
Popis: Introduction Resective epilepsy surgery is often seen as a last resort when treating drug-resistant epilepsy. Positive results on quality of life (QoL) and economic benefits after surgery argue for a less restrictive attitude towards epilepsy surgery for drug-resistant epilepsy. QoL and economic benefits are country-dependent. The objective of the Resective Epilepsy Surgery, QUality of life and Economic evaluation (RESQUE) trial is to evaluate the change in QoL before and after epilepsy surgery in Dutch people with drug-resistant epilepsy. The results will form part of an economic evaluation of epilepsy surgery in people with epilepsy (PWE) in The Netherlands.Methods and analysis A longitudinal prospective multicentre cohort study involving 100 PWE undergoing epilepsy surgery between 2019 and 2025 is being performed in three Dutch academic hospitals. Excluded are PWE who have a lower level of intelligence (TIQ
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