Data supporting the role of Fyn in initiating myelination in the peripheral nervous system

Autor: Yuki Miyamoto, Moe Tamano, Tomohiro Torii, Kazuko Kawahara, Kazuaki Nakamura, Akito Tanoue, Shuji Takada, Junji Yamauchi
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Data in Brief, Vol 7, Iss , Pp 1098-1105 (2016)
Druh dokumentu: article
ISSN: 2352-3409
DOI: 10.1016/j.dib.2016.03.096
Popis: Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])”. Herein we provide the data regarding myelination-related protein markers and myelin ultrastructure in transgenic mice. Keywords: Fyn, Myelination, Peripheral nervous system, Myelin marker protein, Signaling
Databáze: Directory of Open Access Journals