Eliminating Spiked Bovine Spongiform Encephalopathy Agent Activity from Heparin

Autor:	Cyrus Bett, Omozusi Andrews, David M. Asher, Teresa Pilant, David Keire, Luisa Gregori
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	bovine spongiform encephalopathy bovine heparin porcine heparin heparin prions prion protein Medicine Infectious and parasitic diseases RC109-216
Zdroj:	Emerging Infectious Diseases, Vol 26, Iss 10, Pp 2478-2480 (2020)
Druh dokumentu:	article
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2610.200142
Popis:	US manufacturers, concerned about bovine spongiform encephalopathy (BSE), ceased marketing bovine heparin in the 1990s. Recent short supplies of safe porcine heparin suggest that reintroducing bovine heparin might benefit public health. We purified heparin from crude bovine extract spiked with BSE agent, removing substantial infectivity and abnormal prion proteins (PrPTSE).
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d78c1fbc41374b3784f328aa1e795ee8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF