Intracranial Fusarium Fungal Abscess in an Immunocompetent Patient: Case Report and Review of the Literature

Autor: Asa Peterson, Martin H. Pham, Brian Lee, Deborah Commins, Joseph Cadden, Steven L. Giannotta, Gabriel Zada
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Neurological Surgery Reports, Vol 75, Iss 02, Pp e241-e245 (2014)
Druh dokumentu: article
ISSN: 2193-6358
2193-6366
DOI: 10.1055/s-0034-1387182
Popis: Abstract Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare. Case Report An immunocompetent 33-year-old Hispanic woman presented with persistent headaches and was found to have a contrast-enhancing mass in the left petrous apex and prepontine cistern. She underwent a subsequent craniotomy for biopsy and partial resection that revealed a Fusarium abscess. She had a left transient partial oculomotor palsy following the operation that resolved over the next few weeks. She was treated with long-term intravenous antifungal therapy and remained at her neurologic baseline 18 months following the intervention. Discussion To our knowledge, this is the first reported case of Fusarium spp brain abscess in an immunocompetent patient. Treatment options include surgical intervention and various antifungal medications. Conclusion This case demonstrates the rare potential of intracranial Fusarium infection in the immunocompetent host, as well as its successful treatment with surgical aspiration and antifungal therapy.
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