| Autor: |
L. Eichhorn, J. Doerner, J. A. Luetkens, J. M. Lunkenheimer, R. C. Dolscheid-Pommerich, F. Erdfelder, R. Fimmers, J. Nadal, B. Stoffel-Wagner, H. H. Schild, A. Hoeft, B. Zur, C. P. Naehle |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Magnetic Resonance, Vol 20, Iss 1, Pp 1-11 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1532-429X |
| DOI: |
10.1186/s12968-018-0455-x |
| Popis: |
Abstract Background Prolonged breath holding results in hypoxemia and hypercapnia. Compensatory mechanisms help maintain adequate oxygen supply to hypoxia sensitive organs, but burden the cardiovascular system. The aim was to investigate human compensatory mechanisms and their effects on the cardiovascular system with regard to cardiac function and morphology, blood flow redistribution, serum biomarkers of the adrenergic system and myocardial injury markers following prolonged apnoea. Methods Seventeen elite apnoea divers performed maximal breath-hold during cardiovascular magnetic resonance imaging (CMR). Two breath-hold sessions were performed to assess (1) cardiac function, myocardial tissue properties and (2) blood flow. In between CMR sessions, a head MRI was performed for the assessment of signs of silent brain ischemia. Urine and blood samples were analysed prior to and up to 4 h after the first breath-hold. Results Mean breath-hold time was 297 ± 52 s. Left ventricular (LV) end-systolic, end-diastolic, and stroke volume increased significantly (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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