Perfluoroalkanesulfonamide Organocatalysts for Asymmetric Conjugate Additions of Branched Aldehydes to Vinyl Sulfones

Autor: Kosuke Nakashima, Miho Murahashi, Hiroki Yuasa, Mariko Ina, Norihiro Tada, Akichika Itoh, Shin-ichi Hirashima, Yuji Koseki, Tsuyoshi Miura
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Molecules, Vol 18, Iss 12, Pp 14529-14542 (2013)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules181214529
Popis: Asymmetric conjugate additions of branched aldehydes to vinyl sulfones promoted by sulfonamide organocatalyst 6 or 7 have been developed, allowing facile synthesis of the corresponding adducts with all-carbon quaternary stereocenters in excellent yields with up to 95% ee.
Databáze: Directory of Open Access Journals