Microcirculatory parameters as risk factors for predicting progression of posterior staphyloma in highly myopic eyes: a case–control study

Autor: Haoru Li, Nan Gao, Ruixin Li, Luobu Luodian, Jinyuan Sui, Yang Bai, Di Wu, Qing He, Yuxin Wang, Zhiqing Li, Ruihua Wei
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Eye and Vision, Vol 11, Iss 1, Pp 1-12 (2024)
Druh dokumentu: article
ISSN: 2326-0254
DOI: 10.1186/s40662-024-00413-1
Popis: Abstract Background To assess the rate of macular blood flow decreasing in adults with and without posterior staphyloma (PS) using optical coherence tomography angiography (OCTA) and to identify risk factors associated with PS progression. Methods This longitudinal case-control study enrolled 122 eyes of 122 patients—64 patients with PS (PS group) and 58 patients without PS (NPS group). Participants underwent OCTA and clinical examinations at least twice, and those followed for at least one year were included in the analysis. Logistic regression analysis and machine learning were applied to explore the risk factors for PS and its progression. Results Patients in the PS group exhibited faster growth rates of spherical equivalent refraction (SER), axial length (AL), curvature index (CI), and posterior scleral height (PSH) as well as higher loss rates of choriocapillaris perfusion area (CCPA), choroid perfusion area (CPA) and choroidal vascularity index (CVI) compared to the NPS group (all P
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