Toward a Better Understanding of the Role of Helicobacter pylori Infection as a Cause of Dyspepsia

Autor: Frank YH Lin, Philip M Sherman
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Zdroj: Canadian Journal of Gastroenterology, Vol 18, Iss 2, Pp 136-137 (2004)
Druh dokumentu: article
ISSN: 0835-7900
DOI: 10.1155/2004/637534
Popis: The relationship between gastric inflammation caused by Helicobacter pylori infection and symptoms of dyspepsia remains controversial (1). Using a murine model of gastric infection, Bercik et al provide new insights into the mechanism underlying such interactions. Gastric sections from Balb/c mice infected with H pylori, strain SS-1, were used for both histological evaluation and studies of neuromuscular physiology. Acute infection (two weeks) caused an antral-predominant polymorphonuclear cell infiltrate that was superceded by a corpus-predominant mononuclear and macrophage infiltrate in chronic infection (three to 16 months).
Databáze: Directory of Open Access Journals