| Autor: |
Mingguang Zhang, Mei-li Qi, Kunshan Yuan, Hanjie Liu, Jinping Ren, Aihua Liu, Shengkun Yao, Xiangrui Guo, Xiushan Li, Haijun Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Materials Research and Technology, Vol 22, Iss , Pp 728-734 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2238-7854 |
| DOI: |
10.1016/j.jmrt.2022.11.122 |
| Popis: |
Skull defect is a common clinical disease, and the corresponding treatment is still a grand challenge. No artificial product can perfectly integrate with human skull and match the skull defect during growth. Herein, we report a porous polyetheretherketone (PEEK) implant with the microstructures almost identical to natural bones for repairing skull defect. Compared to non-porous PEEK controls, the porous PEEK implants efficiently promote cell adhesion, regenerate skull tissues, and finally achieve perfect healing with surrounding tissues within 6 months. This work suggests the important potential of integrated porous PEEK implants for treating skull defect in clinic, especially for children with rapidly growing skulls. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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