The genetic structure of Pacific Islanders.

Autor: Jonathan S Friedlaender, Françoise R Friedlaender, Floyd A Reed, Kenneth K Kidd, Judith R Kidd, Geoffrey K Chambers, Rodney A Lea, Jun-Hun Loo, George Koki, Jason A Hodgson, D Andrew Merriwether, James L Weber
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: PLoS Genetics, Vol 4, Iss 1, p e19 (2008)
Druh dokumentu: article
ISSN: 1553-7390
1553-7404
DOI: 10.1371/journal.pgen.0040019
Popis: Human genetic diversity in the Pacific has not been adequately sampled, particularly in Melanesia. As a result, population relationships there have been open to debate. A genome scan of autosomal markers (687 microsatellites and 203 insertions/deletions) on 952 individuals from 41 Pacific populations now provides the basis for understanding the remarkable nature of Melanesian variation, and for a more accurate comparison of these Pacific populations with previously studied groups from other regions. It also shows how textured human population variation can be in particular circumstances. Genetic diversity within individual Pacific populations is shown to be very low, while differentiation among Melanesian groups is high. Melanesian differentiation varies not only between islands, but also by island size and topographical complexity. The greatest distinctions are among the isolated groups in large island interiors, which are also the most internally homogeneous. The pattern loosely tracks language distinctions. Papuan-speaking groups are the most differentiated, and Austronesian or Oceanic-speaking groups, which tend to live along the coastlines, are more intermixed. A small "Austronesian" genetic signature (always
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