Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip

Autor: James M. Dunce, Lucy J. Salmon, Owen R. Davies
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Druh dokumentu: article
ISSN: 2399-3642
DOI: 10.1038/s42003-022-03886-9
Popis: The X-ray crystal structures of C-terminal mutants of the coiled-coil protein cancer testis antigen TEX12 in combination with modeling of the TEX12 wild-type dimer reveal the protein’s control of its oligomeric state, which resembles assembly of its complex with synaptonemal complex central element protein SYCE2.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje