| Autor: |
Mohd Mustufa, Ambreen Abbasi, Summaiya Hanif, Zia Ul Haq Bhat, Hina kabeer, Mohammad Jane Alam, Musheer Ahmad, Mohammad Shakir |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Chemistry of Inorganic Materials, Vol 1, Iss , Pp 100011- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2949-7469 |
| DOI: |
10.1016/j.cinorg.2023.100011 |
| Popis: |
Schiff-base fluorescent chemosensor (E)-N-(4-(dimethylamino)benzylidene)quinolone-3-amine (DBQA) was synthesized and characterized by FT-IR,1H NMR,13C NMR, ESI-MS spectrometry and Single X-ray crystallographic studies. The synthesized chemosensor (DBQA) was used for the detection of Fe3+ successfully. UV-visible and fluorescence spectra of (DBQA) exhibits a ratiometric behaviour along with a bathochromic shift upon the successive addition of Fe3+. The fluorescence spectra of chemosensor (DBQA) were recorded followed by addition of concentrations of different metal ions and NH3. The chemosensor (DBQA) showed a favourable linear relationship between the fluorescence intensity and concentration of Fe3+ ion. DBQA exhibits a ratiometric response and illustrates high sensitivity (with a detection limit of 0.4 μM) and good selectivity for the Fe3+ ion over other transition metal ions. DBQA shows 0.6 μM detection limit for NH3 along with ratiometric behaviour also. The association constant (Ka) of chemosensor (DBQA) was found to be 1.455×102 M-1/2 for Fe3+. The mechanism of sensing of the present ratiometric fluorescent chemosensor (DBQA) was explained by ICT (Intra-molecular charge transfer) using DFT calculations. The interaction model of chemosensor (DBQA) with Fe3+ was determined to be 2:1 stoichiometry using Job's plot analysis and ESI-MS spectra which further confirms DFT studies. Moreover, tested DBQA + Fe3+ was showed that remarkable anticancer activity against the HCT116 colon cancer cells by MTT assay. Novelty and importance of DBQA as it can be investigate, test or analyse of detect Fe3+ rapidly as compared to other tested ions. Lastly, DBQA can be investigate, test or analyse of Fe3+ in environmental and biological samples. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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