Genetic variation in the fat mass and obesity-associated gene (FTO) in association with food preferences in healthy adults

Autor: Louise Brunkwall, Ulrika Ericson, Sophie Hellstrand, Bo Gullberg, Marju Orho-Melander, Emily Sonestedt
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Food & Nutrition Research, Vol 57, Iss 0, Pp 1-8 (2013)
Druh dokumentu: article
ISSN: 1654-6628
1654-661X
DOI: 10.3402/fnr.v57i0.20028
Popis: Background: Earlier studies have indicated that the fat mass and obesity-associated gene (FTO) is not only associated with BMI and weight but also with appetite and dietary intake. Objectives: We investigated if the FTO rs9939609 associates with food preferences in healthy adults with no cancer, cardiovascular disease, or diabetes. Additionally, we challenged the question if the associations are modified by obesity status (BMI ≤25 or >25 kg/m2). Design: The analyses are made with 22,799 individuals from the Swedish population-based Malmö Diet and Cancer Cohort Study, who were born between 1923 and 1945. To investigate food preference, 27 food groups conducted from a modified diet history method including a 7-day registration of cooked meals and cold beverages were used in the analyses. Bonferroni correction was used to correct for multiple testing, resulting in a cut-off value for significance level of p
Databáze: Directory of Open Access Journals
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