| Autor: |
Maria Anna Smolle, Wolfgang Helmberg, Eva Maria Matzhold, Dominik Andreas Barth, Nazanin Sareban, Joanna Szkandera, Bernadette Liegl‐Atzwanger, Andreas Leithner, Martin Pichler |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Cancer Medicine, Vol 12, Iss 2, Pp 1237-1246 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2045-7634 |
| DOI: |
10.1002/cam4.4989 |
| Popis: |
Abstract Background Perioperatively administered (leukocyte reduced) allogeneic red blood cell transfusions (lrRBCTs) may lead to transfusion‐related immunomodulation and reduced overall survival (OS) in cancer patients. Herein, the effect of lrRBCT on local recurrence (LR), distant metastasis (DM), and OS in soft tissue sarcoma (STS) patients was analysed. Methods Retrospective study on 432 STS patients (mean age: 60.0 ± 17.8 years; 46.1% female), surgically treated at a tertiary tumour centre. Uni‐ and multivariate survival models were calculated to analyse impact of perioperative lrRBCTs on LR, DM, OS. Results Perioperatively, 75 patients (17.4%) had received lrRBCTs. Older patients, deep, large, lower limb STS rather required lrRBCTs (all p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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