Alzheimer’s disease as an inflammatory disease
| Autor: | Bolós Marta, Perea Juan Ramón, Avila Jesús |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Biomolecular Concepts, Vol 8, Iss 1, Pp 37-43 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1868-5021 1868-503X |
| DOI: | 10.1515/bmc-2016-0029 |
| Popis: | Alzheimer’s disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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