| Autor: |
Ruth Nabisere-Arinaitwe, Lydia Namatende-Sakwa, Josephine Bayiga, Juliet Nampala, Lucy Alinaitwe, Florence Aber, Brian Otaalo, Joseph Musaazi, Rachel King, Mike Kesby, Derek J. Sloan, Christine Sekaggya-Wiltshire |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 33, Iss , Pp 100385- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2405-5794 |
| DOI: |
10.1016/j.jctube.2023.100385 |
| Popis: |
Background: Completion of tuberculosis (TB) treatment presents several challenges to patients, including long treatment duration, medication adverse-effects and heavy pill burden. WHO emphasize the need for patient-centered TB care, but such approaches require understanding of patient experiences and perceptions. Methods: In 2020, we nested a qualitative study within a clinical trial that recruited 128 HIV-TB co-infected adults in Kampala receiving rifampicin-based TB treatment, alongside anti-retroviral therapy. A purposively selected sub-sample of 46 trial participants contributed to nine gender segregated focus group discussions. Of these, 12 also participated in in-depth interviews. Sessions were recorded, transcribed verbatim and translated from local languages into English. Thematic analysis focused on drug adverse-effects, use of self-prescribed medications and barriers to treatment adherence. Results: Patients seemed more concerned about adverse effects that clinicians sometimes overlook such as change in urine color. Those who remembered pre-treatment counselling advice were disinclined to manage adverse-effects by self-prescription. Difficulty in accessing a medical practitioner was reported as a reason for self-medication. Obstacles to adherence included stigma (especially from visible adverse-effects like “red urine”), difficulties with pill size and number, discomfort with formulation and medication adverse effects. Conclusion: Tailored pre-treatment counselling, improved access to clinical services, and simpler drug administration will deliver more patient-centered care. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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