The Effect of Sample Storage Temperature on the Phenytoin Level in Serum

Autor: Paiboon Tummarintra, Phakrop Kaewbundit,, Rasda Boonprasert, Teera Kolladarungkri
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Siriraj Medical Journal, Vol 67, Iss 6, Pp 262-266 (2015)
Druh dokumentu: article
ISSN: 2228-8082
Popis: Objective: To study the effect of temperature on phenytoin concentration in serum and to determine the sample were kept at 2-8°C and 35°C. Methods: Serum samples of patients, who had been treated with phenytoin. had their phenytoin level determined on the first day. The sample was stored for seven days and analyzed on days three, five and seven of the study and divided into three storage concentrations from 2.5-10, 10.1-20 and 20.1-30 μg/ml compared using 50 samples per group. Results: Phenytoin level was found to have increased over time to three days at a temperature of 35°C and five days at 2-8°C. It increased in the level of statistical significance at p
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