| Autor: |
Xihai Zhao, Daniel S. Hippe, Rui Li, Gador M. Canton, Binbin Sui, Yan Song, Feiyu Li, Yunjing Xue, Jie Sun, Kiyofumi Yamada, Thomas S. Hatsukami, Dongxiang Xu, Maoxue Wang, Chun Yuan |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
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| Zdroj: |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 8 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2047-9980 |
| DOI: |
10.1161/JAHA.117.005831 |
| Popis: |
BackgroundCarotid atherosclerotic plaque rupture is an important source of ischemic stroke. However, the prevalence of high‐risk plaque (HRP) defined as plaques with luminal surface disruption, a lipid‐rich necrotic core occupying >40% of the wall, or intraplaque hemorrhage in Chinese population remains unclear. This study uses carotid magnetic resonance imaging (CMRI) to investigate HRP prevalence in carotid arteries of Chinese patients with cerebrovascular symptoms. Methods and ResultsPatients with cerebral ischemic symptoms in the anterior circulation within 2 weeks and carotid plaque determined by ultrasound were recruited and underwent CMRI. The HRP features were identified and compared between symptomatic and asymptomatic arteries. Receiver‐operating‐characteristic analysis was used to calculate area‐under‐the‐curve (AUC) of stenosis and maximum wall thickness for discriminating presence of HRP. In 1047 recruited subjects, HRP detected by CMRI was nearly 1.5 times more prevalent than severe stenosis (≥50%) in this cohort (28% versus 19%, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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