Stevens-Johnson syndrome/toxic epidermal necrolysis overlap triggered by ethosuximide: a rare pediatric report
| Autor: | Sandra Soares-Cardoso, Joana Pimenta, Flávia Belinha, Manuel Salgado, Margarida Rato, Cristina Pereira, Leonor Ramos |
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| Jazyk: | English<br />Portuguese |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Revista da Sociedade Portuguesa de Dermatologia e Venereologia, Vol 81, Iss 2 (2023) |
| Druh dokumentu: | article |
| ISSN: | 2182-2395 2182-2409 |
| Popis: | Introduction: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe and life-threatening mucocutaneous conditions characterized by fever and necrosis of the epidermis. Up to 90% of cases are drug-induced. Antiseizure drugs (ASD) are known to cause SJS, but only a very few ethosuximide-induced SJS cases have been reported in the literature. Case presentation: We report a case of ethosuximide-induced SJS/TEN overlap in a 4-year-old boy, confirmed by patch tests, with improvement with intravenous immunoglobulin (IVIG) and systemic corticosteroid therapy cycle. Conclusion: This case highlights the need to expand knowledge about the optimal treatment strategy for these rare conditions, in addition to supportive treatment. |
| Databáze: | Directory of Open Access Journals |
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