| Autor: |
Simon A. Herbert, Laura J. van Laeren, Dominic C. Castell, Gareth E. Arnott |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2751-2755 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1860-5397 |
| DOI: |
10.3762/bjoc.10.291 |
| Popis: |
The diastereoselective oxazoline-directed lithiation of calix[4]arenes is reported with diastereoselective ratios of greater than 100:1 in some instances. Notably, it has been found that the opposite diastereomer can be accessed via this approach merely through the choice of an alkyllithium reagent. The inherently chiral oxazoline calix[4]arenes have also been preliminarily examined as ligands in the palladium-catalyzed Tsuji–Trost allylation reaction, returning results comparable to their planar chiral ferrocene counterparts pointing towards future application of these types of compounds. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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