| Autor: |
Chen-Chung Liu, Jia-Chi Shan, Chih-Lin Chiang, Ming H. Hsieh, Chih-Min Liu, Yi-Ling Chien, Shao-Chien Chen, Tzung-Jeng Hwang |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Journal of the Formosan Medical Association, Vol 114, Iss 6, Pp 539-545 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
0929-6646 |
| DOI: |
10.1016/j.jfma.2013.01.004 |
| Popis: |
The debate on whether long-acting injectable antipsychotic (LAIA) medication is superior to oral medication, in preventing rehospitalization of patients with schizophrenia, remains inconclusive. We compared rehospitalization rates over 3 years following discharge from an acute admission, in which patients either began using LAIAs regularly for the first time, or continued to use oral antipsychotics. Methods: A retrospective observational study of 92 inpatients with schizophrenia from a university-based medical center during 2004–2008. The primary outcome measure is the rehospitalization rates between groups, as estimated by Kaplan-Meier survival analysis. Results: Eighteen of 47 (38.3%) LAIA patients, and 16 of 45 (35.6%) oral medication patients were rehospitalized (average time to rehospitalization, 378 ± 262 vs. 378 ± 340 days; p = 0.997). The estimated cumulative rates of rehospitalization were similar between groups. The overall odds comparing the LAIA to the oral medication group were 1.085 ± 0.373 (95% confidence interval: 0.553–2.13, p = 0.813). Compared to the oral medication group, the LAIA group had fewer coded with sufficient previous treatment response (32% vs. 69%, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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