Association of Leukocyte Telomere Length with Oxidative Stress in Yoga Practitioners

Autor: Bandi Hari Krishna, Gorantla Shravya Keerthi, Chintala Kiran Kumar, Natham Mallikarjuna Reddy
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Clinical and Diagnostic Research, Vol 9, Iss 3, Pp CC01-CC03 (2015)
Druh dokumentu: article
ISSN: 2249-782X
0973-709X
DOI: 10.7860/JCDR/2015/13076.5729
Popis: Objective: Yoga is a mind-body modulation technique that has been shown to have beneficial effects on various diseases related to various systems in the body. However, the molecular basis of mechanism of action is not clear. Hence, this study was designed to study the leukocyte telomere biology and its relation with homocysteine and oxidative stress in yoga practitioners. Materials and Methods: This is a prospective case-control study involving Yoga practitioners aged 30–40 y with minimum of two years yoga practice (Yoga group) and age, gender and body mass index matched sedentary healthy general population with no medical problems (Control group). Leukocyte telomere length (LTL) was measured by using quantitative PCR (qPCR), fasting plasma homocysteine was measured by a rapid highperformance liquid chromatography assay and the oxidative stress was assessed with total antioxidant status (TAOS), malondialdehyde (MDA) measured by colorimetry. Results: The LTL was shorter in control group than in yoga group (p
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