Ethiopian coffee (Coffea arabica) improves glucose uptake and modulates metabolic enzyme activities linked to hyperglycemia-induced infertility in isolated rats’ testes

Autor: Almahi I. Mohamed, Kolawole A. Olofinsan, Veronica F. Salau, Ochuko L. Erukainure, Md. Shahidul Islam
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Food Production, Processing and Nutrition, Vol 6, Iss 1, Pp 1-16 (2024)
Druh dokumentu: article
ISSN: 2661-8974
DOI: 10.1186/s43014-024-00247-3
Popis: Abstract The present study evaluated the inhibitory effect of Ethiopian coffee (Coffea arabica) on carbohydrate digestive enzymes and its protective effect against glucose-induced testicular dysfunction using in vitro and in silico study models. Testicular oxidative stress was initiated by co-incubating testocular tissue collected from male Sprague-Dawley rats in glucose solution with different concentrations of Ethiopian coffee aqueous extracts (hot and cold) for 2 h at 37ºC. Glucose-mediated oxidative stress significantly (p
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