The Role of Pelvic Exenteration in Cervical Cancer: A Review of the Literature

Autor: Ana Carla Franco Ubinha, Priscila Grecca Pedrão, Aline Cássia Tadini, Ronaldo Luis Schmidt, Marcelo Henrique dos Santos, Carlos Eduardo Mattos da Cunha Andrade, Adhemar Longatto Filho, Ricardo dos Reis
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Cancers, Vol 16, Iss 4, p 817 (2024)
Druh dokumentu: article
ISSN: 2072-6694
DOI: 10.3390/cancers16040817
Popis: Pelvic exenteration represents a radical procedure aimed at achieving complete tumor resection with negative margins. Although it is the only therapeutic option for some cases of advanced tumors, it is associated with several perioperative complications. We believe that careful patient selection is related to better oncologic outcomes and lower complication rates. The objectives of this review are to identify the most current indications for this intervention, suggest criteria for case selection, evaluate recommendations for perioperative care, and review oncologic outcomes and potential associated complications. To this end, an analysis of English language articles in PubMed was performed, searching for topics such as the indication for pelvic exenteration for recurrent gynecologic neoplasms selection of oncologic cases, the impact of tumor size and extent on oncologic outcomes, preoperative and postoperative surgical management, surgical complications, and outcomes of overall survival and recurrence-free survival.
Databáze: Directory of Open Access Journals
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