Prognosis of patients with systemic lupus erythematosus and discoid lesions

Autor:	Thelma Larocca Skare, Barbara Stadler, Emilio Weingraber, Diogo F. De Paula
Jazyk:	English<br />Portuguese
Rok vydání:	2013
Předmět:	Glomerulonephritis Lupus erythematosus cutaneous Lupus erythematosus discoid Lupus erythematosus systemic Glomerulonefrite Lupus eritematoso cutaneo Lupus eritematoso discoide Lupus eritematoso sistemico Dermatology RL1-803
Zdroj:	Anais Brasileiros de Dermatologia, Vol 88, Iss 5, Pp 755-758 (2013)
Druh dokumentu:	article
ISSN:	0365-0596 1806-4841
DOI:	10.1590/abd1806-4841.20132042
Popis:	BACKGROUND: It has been observed that patients with systemic lupus erythematosus and discoid lesions have a milder systemic disease. OBJECTIVE: To compare the clinical, demographic and autoantibody profile of systemic lupus erythematosus patients with and without discoid lesions. METHODS: We carried out a retrospective study involving 288 systemic lupus erythematosus patients who met at least four classification criteria of the American College of Rheumatology for systemic lupus erythematosus, comparing the clinical, serological and demographic factors between patients with and without discoid manifestations. RESULTS: Of the 288 patients, 13.8% had discoid lesions. Univariate analysis found no differences in the prevalence of malar rash, photosensitivity, arthritis, serositis, leukopenia, lymphopenia and hemolytic anemia or anemia of the central nervous system (p = ns). Renal lesions were more common in those without discoid lesions (p =0.016), and hemolysis (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/7735ff6ed71548589870e71a39ac1038 Zobrazit plný text záznamu View record in DOAJ