| Autor: |
Hans-Peter Hauber, Meri K Tulic, Anne Tsicopoulos, Benoit Wallaert, Ron Olivenstein, Patrick Daigneault, Qutayba Hamid |
| Jazyk: |
angličtina |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Canadian Respiratory Journal, Vol 12, Iss 1, Pp 13-18 (2005) |
| Druh dokumentu: |
article |
| ISSN: |
1198-2241 |
| DOI: |
10.1155/2005/648984 |
| Popis: |
BACKGROUND: Cystic fibrosis (CF) is a lung disease characterized by chronic infection with Gram-negative bacteria Pseudomonas aeruginosa and Gram-positive bacteria Staphylococcus aureus. Recently, toll-like receptor (TLR) 4 has been shown to be responsible for the lipopolysaccharide (LPS)-mediated immune response. While TLR2 mediates responses driven by bacterial lipoproteins and peptidoglycans from Gram-positive bacteria, LPS derived from P aeruginosa may stimulate the immune response in the airways of patients with CF via activation of TLR4. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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