Preparation of a Key Intermediate for the Angiotensin II Antagonist Losartan via Vilsmeier Chloroformylation

Autor: Gareth J. Griffiths
Jazyk: German<br />English<br />French
Rok vydání: 1997
Předmět:
Zdroj: CHIMIA, Vol 51, Iss 6 (1997)
Druh dokumentu: article
ISSN: 0009-4293
2673-2424
Popis: A novel preparation of 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde, a key intermediate for the synthesis of the angiotensin II antagonist Losartan potassium, via Vilsmeier chloroformylation of imidazolinone is described.
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