Preparation of a Key Intermediate for the Angiotensin II Antagonist Losartan via Vilsmeier Chloroformylation
Autor: | Gareth J. Griffiths |
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Jazyk: | German<br />English<br />French |
Rok vydání: | 1997 |
Předmět: | |
Zdroj: | CHIMIA, Vol 51, Iss 6 (1997) |
Druh dokumentu: | article |
ISSN: | 0009-4293 2673-2424 |
Popis: | A novel preparation of 2-butyl-5-chloro-3H-imidazole-4-carbaldehyde, a key intermediate for the synthesis of the angiotensin II antagonist Losartan potassium, via Vilsmeier chloroformylation of imidazolinone is described. |
Databáze: | Directory of Open Access Journals |
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