Differences in treatment response to a total diet replacement intervention versus a food‐based intervention: A secondary analysis of the OPTIWIN trial

Autor: Jamy D. Ard, Kristina H. Lewis, Sarah S. Cohen, Amy E. Rothberg, Sally L. Coburn, Judy Loper, Laura Matarese, Walter J. Pories, Seletha Periman
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Obesity Science & Practice, Vol 6, Iss 6, Pp 605-614 (2020)
Druh dokumentu: article
ISSN: 2055-2238
DOI: 10.1002/osp4.444
Popis: Summary Objective For every weight loss treatment, there are usually groups of people who lose less than expected. This study sought to determine if response rates to a total diet replacement (TDR) differed from those of a calorie‐restricted, food‐based (FB) diet. Methods Data from OPTIWIN, a 12‐month multicenter trial in adults with a BMI of 30–55 kg/m2, with 26‐week weight‐loss and weight‐maintenance phases, were utilized. Participants (n = 330) were randomized to the OPTIFAST programme (OP) or to a reduced‐energy FB diet. Treatment non‐responders were defined as those who lost
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