Chemically Diverse and Biologically Active Secondary Metabolites from Marine Phylum chlorophyta

Autor: Sayed Asmat Ali Shah, Syed Shams ul Hassan, Simona Bungau, Yongsheng Si, Haiwei Xu, Md. Habibur Rahman, Tapan Behl, Daniela Gitea, Flavia-Maria Pavel, Raluca Anca Corb Aron, Bianca Pasca, Sebastian Nemeth
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Marine Drugs, Vol 18, Iss 10, p 493 (2020)
Druh dokumentu: article
ISSN: 1660-3397
DOI: 10.3390/md18100493
Popis: For a long time, algal chemistry from terrestrial to marine or freshwater bodies, especially chlorophytes, has fascinated numerous investigators to develop new drugs in the nutraceutical and pharmaceutical industries. As such, chlorophytes comprise a diverse structural class of secondary metabolites, having functional groups that are specific to a particular source. All bioactive compounds of chlorophyte are of great interest due to their supplemental/nutritional/pharmacological activities. In this review, a detailed description of the chemical diversity of compounds encompassing alkaloids, terpenes, steroids, fatty acids and glycerides, their subclasses and their structures are discussed. These promising natural products have efficiency in developing new drugs necessary in the treatment of various deadly pathologies (cancer, HIV, SARS-CoV-2, several inflammations, etc.). Marine chlorophyte, therefore, is portrayed as a pivotal treasure in the case of drugs having marine provenience. It is a domain of research expected to probe novel pharmaceutically or nutraceutically important secondary metabolites resulting from marine Chlorophyta. In this regard, our review aims to compile the isolated secondary metabolites having diverse chemical structures from chlorophytes (like Caulerpa ssp., Ulva ssp., Tydemania ssp., Penicillus ssp., Codium ssp., Capsosiphon ssp., Avrainvillea ssp.), their biological properties, applications and possible mode of action.
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