Primary Hodgkin’s Lymphoma of the Breast Initially Treated by Surgical Excision and Axillary Dissection

Autor: Ingrid Marton, Zlatko Hrgović, Dubravko Habek
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Acta Clinica Croatica, Vol 59., Iss 2., Pp 365-367 (2020)
Druh dokumentu: article
ISSN: 0353-9466
1333-9451
DOI: 10.20471/acc.2020.59.02.22
Popis: Primary breast lymphoma accounts for 0.04%-0.5% of all breast malignancies. Primary non-Hodgkin’s lymphomas of the breast are extremely rare and represent approximately 0.38%-0.7% of all cases. Epstein-Barr virus (EBV) has been postulated to play an important role in the pathogenesis of Hodgkin’s lymphoma. We present a case of EBV-positive primary Hodgkin’s lymphoma of the breast. Although there is no sufficient data on this challenging diagnosis, it is known that it could be misdiagnosed with inflammatory breast carcinoma. A crucial part of the proper histopathologic diagnosis is immunohistochemistry. Different modalities of treatment include operative procedure, chemotherapy and radiotherapy. Recent studies suggest chemotherapy and radiotherapy to be initial treatment for patients with primary breast lymphomas.
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