Identification of genetic variants by whole genome sequencing in Ankamali pigs of Kerala
| Autor: | Michelle Elizabeth Roy, M. Manoj, P.M. Rojan, Tina Sadan, T.V. Aravindakshan, A.P. Usha, M.P. Unnikrishnan |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Veterinary and Animal Sciences, Vol 54, Iss 2, Pp 524-531 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0971-0701 2582-0605 |
| DOI: | 10.51966/jvas.2023.54.2.524-531 |
| Popis: | Ankamali pig is a domesticated native variety of Kerala which is well known for its disease resistance, lean meat and adaptability to hot tropical environments. Recent breakthrough in genome sequencing technologies have created unparalleled prospects to characterize individual genomic landscapes and identifying mutations between and within populations. The current study aims to determine the genetic variations in Ankamali pigs using whole genome sequencing. The GATK HaplotypeCaller was used to identify the variants. There were over 26 million (26,604,589) single nucleotide variants (SNVs), including more than 21 million SNPs and over 5 million indels. In Ankamali pigs, the total genome length obtained was more than 2.5 billion with an average variant rate of one variant in every 94 bases. The significance of different variant rate on 18 chromosomes were analysed using the chi-square statistics. The variant rates in Sus scrofa chromosomes10 and 13 were significantly different (p |
| Databáze: | Directory of Open Access Journals |
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