FDG PET/CT in the evaluation of a rare case of multisystem involvement in newly diagnosed Rosai–Dorfman–Destombes disease

Autor: Ahmed Fathala, Jameela Edathodu, Nasir Bakshi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Saudi Journal of Medicine and Medical Sciences, Vol 9, Iss 2, Pp 195-198 (2021)
Druh dokumentu: article
ISSN: 1658-631X
DOI: 10.4103/sjmms.sjmms_99_20
Popis: Rosai–Dorfman–Destombes disease (RDD) is a rare histocytic disorder with a broad spectrum of clinical presentations. The disease typically presents with lymphadenopathy but may involve multiple systems. Usually, RDD lesions demonstrate intense [18]F-Fluorodeoxyglucose (FDG) uptake in positron emission tomography/computed tomography (PET/CT) imaging due to the inflammation and infiltration with high metabolic process of the disease. Here, we describe a rare case of 37-year-old man who presented with multiple systemic symptoms, including fever, weight loss and bilateral cervical, and inguinal lymphadenopathy who underwent FDG PET/CT for detection of disease extension. This case highlights the role of FDG PET/CT in establishing the disease extent in newly diagnosed RDD and guiding the therapeutic recommendations and for follow-up to monitor the disease response to therapy. To the best of our knowledge, this is the first case report from Saudi Arabia highlighting the role of FDG PET/CT in newly diagnosed RDD.
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